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Constipation from Chemotherapy & Pain Medications  

Why do some chemotherapy drugs and certain pain medications cause constipation?

Constipation can occur as a side effect of certain types of chemotherapy and certain types of pain medications.[1] Some types of chemotherapy and certain pain medications can cause a decrease in the wave-like movement (i.e., peristalsis) of the intestines that otherwise move matter to be excreted from the body. Decreased peristalsis results in the formation of hard, dry stools that take longer to travel through the intestine and are more difficult to be excreted.

Common symptoms of constipation include:[1]

• Small stools
• Hard, dry stools
• Difficulty in having a bowel movement
• Reduced frequency of bowel movements compared to what previously was normal for the patient

Other symptoms that may accompany constipation include: [1]

• Cramps or pressure in the lower part of the abdomen
• Gas (flatulence)

Habits that can make constipation from chemotherapy or pain medications worse include:[1]

• Lack of sufficient consumption of fluids
• Improper diet
• Low level of physical activity

A possible complication of constipation is impaction of the stools, which is a condition in which the stools do not move through the colon or the rectum.[1]

For information on prevention and treatment of constipation, see our Q&A called, "Is there anything I can do to prevent and relieve constipation from the chemotherapy drugs and pain medications I am taking?

REFERENCE

1. Managing Constipation. Accessed at www.chemotherapy.com.





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