Peripheral neuropathy involves sensations of tingling and numbness in the extremities (i.e., the arms, hands, legs, and feet) and related symptoms.[1] Although peripheral neuropathy can be caused by certain illnesses, it is a possible side effect of certain chemotherapy drugs damaging nerves that send the following types of signals:
• Transmissions about muscle movement sent by the central nervous system (CNS) to the extremities
• Sensation in the extremities transmitted to the CNS
Types of symptoms of peripheral neuropathy may include:[1]
• Tingling (called paresthesia) or tickling sensation in the extremities
• Prickling sensation in the extremities
• Burning sensation in the extremities
• Other types of discomfort and pain in the extremities
• Numbness in the extremities
• Weakness of the extremities
Symptoms of peripheral neuropathy of the extremities often begin at the end of the extremity, such as the fingers and toes, and slowly extend up the extremity.[1]
The intensity and duration of peripheral neuropathy varies with the different types of chemotherapy drugs, doses, and patients.[1] Possible long-term (i.e., chronic) complications of peripheral neuropathy of an extremity include:
• Impairment of ability to feel in the extremity
• Deterioration (i.e., atrophy) of muscles in the extremity
• Muscle weakness in the extremity
• Impairment of ability to move the extremity
Some patients experience chronic peripheral neuropathy, whereas other patients experience a slow recovery from the condition.[1] Recovery from peripheral neuropathy may be partial or complete.
Prompt treatment of peripheral neuropathy is very important to increase the likelihood and extent of recovery.[1] If you are experiencing symptoms of peripheral neuropathy, notify your oncologist immediately. See our Q&A called, "Is there anything that can be done to treat peripheral neuropathy from chemotherapy?"
REFERENCE
1. Managing numbness and tingling (peripheral neuropathy). Accessed at www.chemotherapy.com.
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