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Toxicity  

What does toxicity mean?

Toxicity means a destructive effect on cells.

Chemotherapy (i.e., the use of chemo drugs) can be a very effective part of the treatment of breast cancer. Chemotherapy drugs work by having destructive (i.e., toxic) effects on cells that divide rapidly, such as cancer cells. The toxic effects on cancer cells are a part of the toxicity (and rationale for use) of chemotherapy drugs.

However, cancer cells are not the only cells that divide rapidly in the body. For example, normal cells in the bone marrow, cells lining the intestine, and cells in hair follicles also divide rapidly. Unfortunately, the production of healthy cells in these parts of the body also may be affected by certain types of chemotherapy drugs.

Because some chemotherapy drugs can affect the production of healthy cells in these parts of the body, the effect on healthy cells and the symptoms that result also are called a toxic effect, an adverse effect, or a side effect. Thus, the toxic effects on healthy cells are a part of the toxicity of chemotherapy drugs.

Be sure to tell your oncologist if you are experiencing any side effects during chemotherapy. Various medicines and other therapies are available to minimize and manage many of side effects of chemotherapy. See our Q&As on the specific side effect and its management and treatment.

Most of the side effects of chemotherapy usually go away during the recovery period portion of the chemotherapy cycle or after all of the chemotherapy treatment has been completed. Consult your oncologist if you are experiencing any of side effects during the recovery period part of the chemotherapy cycle or after all of the chemotherapy treatment has been completed. Various types of medications and other forms of therapy are available for management of side effects that persist past the completion of chemotherapy.


Questions Related to Toxicity
Why does taking chemotherapy put me at higher risk for having infections?
Is there anything that can be done to lessen the chance of infections during chemotherapy?
Is there anything that can be done to treat the neutropenia and prevent the infections that I am experiencing due to chemotherapy?
What is granulocyte colony-stimulating factor (G-CSF)?
What is Neulasta?
What is pegfilgrastim?
What is thrombocytopenia?
Is there anything that can be done to treat the thrombocytopenia that I am experiencing due to chemotherapy?
What is Neumega?
What is oprelvekin?
What is interleukin-11?
What is Aranesp?
What is darbepoetin?
Why am I experiencing fatigue during my chemotherapy treatment?
What does the term, side effects, mean?
Can I have children after my treatment for breast cancer?
What is chemo brain?
Why does chemotherapy cause hair loss?
What is mucositis?
Why does chemotherapy cause diarrhea?
Why does chemotherapy and certain pain medications cause nausea and vomiting?
Why do some chemotherapy drugs and certain pain medications cause constipation?
Is there anything I can do to prevent and relieve constipation from the chemotherapy drugs and pain medications I am taking?
What is peripheral neuropathy?
Is there anything that can be done to treat peripheral neuropathy from chemotherapy?
What is transcutaneous nerve stimulation (TENS)?
Can acupuncture help relieve any side effects from chemotherapy and other treatments of breast cancer?
Are there any herbs that can help relieve side effects of treatment of breast cancer?
What is myelosuppression?
I am considering having a mastectomy. What are my options for restoring the appearance of a breast after the mastectomy?
What is xerostomia?
What is dry mouth?
Is there anything that I can do to prevent and treat xerostomia from chemotherapy?
Is there anything that I can do to prevent and treat dry mouth from chemotherapy?
Are there any vitamins and minerals that I can take to help prevent or manage the side effects of cancer treatment?
What are adjuncts?
Is there anything that can be done to relieve the pain I am experiencing during treatment of breast cancer?
What are analgesics?
Is there anything that I can do to manage the sleepiness from pain medications?
What is patient-controlled analgesia?
What is an adverse effect?
What is an adverse event?
What is palmar-plantar erythrodysesthesia?
What is hand and foot syndrome?
What are the surgical options for breast reconstruction after a partial or complete mastectomy?
What is tissue flap surgery?
Are there any side effects with letrozole?
Are there any side effects with Femara?
What is transverse rectus abdominus muscle flap surgery?
What is TRAM flap surgery?

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