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Ovarian Ablation
 
  


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Ovarian Ablation  

What is ovarian ablation? How is it performed?

Ovarian ablation is the stopping of the secretion of sex hormones (e.g., estrogen) by the ovaries in order to treat some women with hormone-dependent breast cancer of Stage I and higher. The cessation of the secretion of sex hormones by the ovaries helps to prevent stimulation of the growth of hormone-dependent breast cancer.

Options for ovarian ablation as adjuvant (post-surgical treatment) include:

Treatment with drugs that work in a manner similar to that of luteinizing hormone-releasing hormone (LHRH), which is also called gonadotropin-releasing hormone (GnRH). Buserelin and goserelin are examples of such drugs. Normally LHRH (GnRH) controls the secretion of the sex hormones, luteinizing hormone and follicle-stimulating hormone by the pituitary gland.

Radiation treatment of the ovaries

Surgical removal of the ovaries (by a procedure called oophorectomy)


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